Edctp -European & Developing Countries Clinical Trials Partnership: Rapid and Accurate Diagnosis of Paediatric Tb

The use of urinary lateral-flow lipoarabinomannan assays for TB diagnosis in children

I Sabi, L Olbrich, W Olomi, A Mfinanga, HJ Zar, MP Nicol, Z Franckling-Smith, C Khosa, D Banze, M Nliwasa, EL Corbett, R Semphere, VP Verghese, JS Michael, L Larsson, SM Graham, R Song, P Nabeta, A Trollip, M Hoelscher

2026-01-01

BACKGROUND: Detection of lipoarabinomannan (LAM) in urine is a promising non-sputum-based test for TB. We aimed to evaluate Fujifi..

Sequential and parallel testing for microbiological confirmation of tuberculosis disease in children in five low-income and middle-income countries: a secondary analysis of the RaPaed-TB study.

Laura Olbrich, Zoe Franckling-Smith, Leyla Larsson, Issa Sabi, Nyanda Elias Ntinginya, Celso Khosa, Denise Banze, Marriott Nliwasa, Elizabeth Lucy Corbett, Robina Semphere, Valsan Philip Verghese, Joy Sarojini Michael, Marilyn Mary Ninan, Elmar Saathoff, Timothy Daniel McHugh, Alia Razid, Stephen Michael Graham, Rinn Song, Pamela Nabeta, Andre Trollip

2024-09-20

BACKGROUND: Despite causing high mortality worldwide, paediatric tuberculosis is often undiagnosed. We aimed to investigate optima..

Rapid and Accurate Diagnosis of Pediatric Tuberculosis Disease: A Diagnostic Accuracy Study for Pediatric Tuberculosis

L Olbrich, M Nliwasa, I Sabi, NE Ntinginya, C Khosa, D Banze, EL Corbett, R Semphere, VP Verghese, JS Michael, SM Graham, U Egere, HS Schaaf, J Morrison, TD Mchugh, R Song, P Nabeta, A Trollip, C Geldmacher, M Hoelscher

2023-05-01

Introduction: An estimated 1.2 million children develop tuberculosis (TB) every year with 240,000 dying because of missed diagnosi..